1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) EC#: 1.5.1.21; ChemWhat Code: 1374383
| Product Name | 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) |
| Example Structure |  |
| Synonyms | 1,2-didehydropipecolate reductase, 1,2-didehydropipecolic reductase, CRYM, DELTA1-piperideine-2-carboxylate reductase, DELTA1-piperideine-2-carboxylate/DELTA1-pyrroline-2-carboxylate reductase, DELTA1-pyrroline-2-carboxylate reductase, DpkA, EC 1.5.1.14, ketimine reductase, L-pipecolate:NADP+ 2-oxidoreductase, lhpD, mu-crystallin, NAD(P)H-dependent DELTA1-pyrroline-2-carboxylate reductase, P2C reductase, P2C/Pyr2C reductase, PaLhpD, Pip2CR, Pyr2C reductase, Pyr2C/Pip2C reductase, reductase, DELTA 1-piperideine-2-carboxylate |
| EC Number | 1.5.1.21 |
| CAS Registry Number | 52037-88-4 |
| Comments | The enzyme is involved in the catabolism of D-lysine and D-proline in bacteria that belong to the Pseudomonas genus. In contrast to EC 1.5.1.1, 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H], which shows similar activity with NADPH and NADH, this enzyme is specific for NADPH. |
| Cofactor | |
| History | |
| Reactions | (1) L-pipecolate + NADP(+) = 1-piperideine-2-carboxylate + Nadph. (2) L-proline + NADP(+) = 1-pyrroline-2-carboxylate + Nadph. |
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