1-pyrroline-2-carboxylate reductase [NAD(P)H] EC#: 1.5.1.49; ChemWhat Code: 1374426
| Product Name | 1-pyrroline-2-carboxylate reductase [NAD(P)H] |
| Example Structure | ![Example Structure of 1-pyrroline-2-carboxylate reductase [NAD(P)H] EC#: 1.5.1.49](/wp-content/uploads/enzyme-structure/1.5.1.49.jpg) |
| Synonyms | LhpH |
| EC Number | 1.5.1.49 |
| CAS Registry Number | |
| Comments | The enzyme from the bacterium Colwellia psychrerythraea is involved in trans-3-hydroxy-L-proline metabolism. In contrast to EC 1.5.1.1, 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H], which shows similar activity with 1-piperideine-2-carboxylate and 1-pyrroline-2-carboxylate, this enzyme is specific for the latter. While the enzyme is active with both NADH and NADPH, activity is higher with NADPH. |
| Cofactor | |
| History | |
| Reactions | L-proline + NAD(P)(+) = 1-pyrroline-2-carboxylate + NAD(P)H. |
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