11-cis-retinol dehydrogenase EC#: 1.1.1.315; ChemWhat Code: 1373426

Product Name 11-cis-retinol dehydrogenase
Example Structure Example Structure of 11-cis-retinol dehydrogenase EC#: 1.1.1.315
Synonyms isethionate formation, reductase D, IsfD, IsfD2, NADPH-dependent sulfoacetaldehyde reductase
EC Number 1.1.1.315
CAS Registry Number
Comments This enzyme, abundant in the retinal pigment epithelium, catalyses the reduction of 11-cis-retinol to 11-cis-retinal [1] while the substrate is bound to the retinal-binding protein [4]. This is a crucial step in the regeneration of 11-cis-retinal, the chromophore of rhodopsin. The enzyme can also accept other cis forms of retinol [2].
Cofactor
History
Reactions 11-cis-retinol-[retinal-binding-protein] + NAD(+) = 11-cis-retinal- [retinol-binding-protein] + Nadh.

Buy Reagent

No reagent supplier? Send quick inquiry to ChemWhat
Want to be listed here as a reagent supplier? (Paid service) Click here to contact ChemWhat

Approved Manufacturers

Want to be listed as an approved manufacturer (Requires approvement)? Please download and fill out this form and send back to approved-manufacturers@chemwhat.com

Contact Us for Other Help

Contact us for other information or services Click here to contact ChemWhat