1,2-dehydroreticulinium reductase (NADPH) EC#: 1.5.1.27; ChemWhat Code: 1374391
| Product Name | 1,2-dehydroreticulinium reductase (NADPH) |
| Example Structure |  |
| Synonyms | 1,2-Dehydroreticuline reductase, 1,2-Dehydroreticulinium ion reductase, DRR, NADPH 1,2-dehydroreticuline reductase, PrDRR, PsDRR1, PsREPI, Reductase, 1,2-dehydroreticuline, reticuline epimerase, STORR |
| EC Number | 1.5.1.27 |
| CAS Registry Number | 130590-58-8 |
| Comments | Reduces the 1,2-dehydroreticulinium ion to (R)-reticuline, which is a direct precursor of morphinan alkaloids in the poppy plant. The enzyme does not catalyse the reverse reaction to any significant extent under physiological conditions. |
| Cofactor | |
| History | |
| Reactions | (R)-reticuline + NADP(+) = 1,2-dehydroreticulinium + Nadph. |
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