1,3,6,8-tetrahydroxynaphthalene synthase EC#: 2.3.1.233; ChemWhat Code: 1377057

Product Name 1,3,6,8-tetrahydroxynaphthalene synthase
Example Structure Example Structure of 1,3,6,8-tetrahydroxynaphthalene synthase EC#: 2.3.1.233
Synonyms 1,3,6,8-tetrahydroxynaphthalene synthase, PhlD, PKS, PKS III, PKS1, RppA, SCO1206, THN synthase, THNS, type III polyketide synthase
EC Number 2.3.1.233
CAS Registry Number
Comments Isolated from the fungus Colletotrichum lagenarium [1], and the bacteria Streptomyces coelicolor [2,3] and Streptomyces peucetius [4]. It only uses malonyl-CoA, without invovement of acetyl-CoA.
Cofactor
History
Reactions 5 malonyl-CoA = 1,3,6,8-tetrahydroxynaphthalene + 5 CoA + 5 CO(2) + H(2)O.

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