1,3,6,8-tetrahydroxynaphthalene synthase EC#: 2.3.1.233; ChemWhat Code: 1377057
| Product Name | 1,3,6,8-tetrahydroxynaphthalene synthase |
| Example Structure |  |
| Synonyms | 1,3,6,8-tetrahydroxynaphthalene synthase, PhlD, PKS, PKS III, PKS1, RppA, SCO1206, THN synthase, THNS, type III polyketide synthase |
| EC Number | 2.3.1.233 |
| CAS Registry Number | |
| Comments | Isolated from the fungus Colletotrichum lagenarium [1], and the bacteria Streptomyces coelicolor [2,3] and Streptomyces peucetius [4]. It only uses malonyl-CoA, without invovement of acetyl-CoA. |
| Cofactor | |
| History | |
| Reactions | 5 malonyl-CoA = 1,3,6,8-tetrahydroxynaphthalene + 5 CoA + 5 CO(2) + H(2)O. |
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