1,3,7-trimethyluric acid 5-monooxygenase EC#: 1.14.13.212; ChemWhat Code: 1375454

Product Name 1,3,7-trimethyluric acid 5-monooxygenase
Example Structure Example Structure of 1,3,7-trimethyluric acid 5-monooxygenase EC#: 1.14.13.212
Synonyms NADH-dependent trimethyluric acid monooxygenase, tmuM
EC Number 1.14.13.212
CAS Registry Number
Comments The enzyme, characterized from the bacterium Pseudomonas sp. CBB1, is part of the bacterial C-8 oxidation-based caffeine degradation pathway. The product decomposes spontaneously to a racemic mixture of 3,6,8-trimethylallantoin. The enzyme shows no acitivity with urate. cf. EC 1.14.13.113, FAD-dependent urate hydroxylase.
Cofactor
History
Reactions 1,3,7-trimethylurate + Nadh + O(2) = 1,3,7-trimethyl-5-hydroxyisourate + NAD(+) + H(2)O.

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