1,4-dihydroxy-2-naphthoyl-CoA synthase EC#: 4.1.3.36; ChemWhat Code: 1382172
| Product Name | 1,4-dihydroxy-2-naphthoyl-CoA synthase |
| Example Structure |  |
| Synonyms | 1,4-dihydroxy-2-naphthoate synthetase, 1,4-dihydroxy-2-naphthoyl coenzyme A synthase, 1,4-dihydroxy-2-naphthoyl-CoA synthase, 1,4-dihydroxy-2-naphthoyl-coenzyme synthase, DHNA synthetase, DHNA-CoA synthase, dihydroxynaphthoate synthase, Dihydroxynaphthoic acid synthetase, MenB, naphthoate synthase, naphthoate synthase (MenB), Rv0548c, synthase, 1,4-dihydroxy-2-naphthoate |
| EC Number | 4.1.3.36 |
| CAS Registry Number | 61328-42-5 |
| Comments | This enzyme is involved in the synthesis of 1,4-dihydroxy-2-naphthoate, a branch point metabolite leading to the biosynthesis of menaquinone (vitamin K2, in bacteria), phylloquinone (vitamin K1?in plants), and many plant pigments. The coenzyme A group is subsequently removed from the product by EC?3.1.2.28, 1,4-dihydroxy-2-naphthoyl-CoA hydrolase. |
| Cofactor | |
| History | |
| Reactions | 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA = 1,4-dihydroxy-2-naphthoyl-CoA + H(2)O. |
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