16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase EC#: 2.1.1.182; ChemWhat Code: 1376397

Product Name 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase
Example Structure Example Structure of 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase EC#: 2.1.1.182
Synonyms 16S rRNA adenine dimethyltransferase, KsgA, ksgA methyltransferase, RsmA, S-adenosylmethionine-6-N’,N’-adenosyl (rRNA) dimethyltransferase
EC Number 2.1.1.182
CAS Registry Number
Comments KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine1518 and adenine1519 in 16S rRNA. Strains lacking the methylase are resistant to kasugamycin [1].
Cofactor
History
Reactions 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)- dimethyladenine(1519) in 16S rRNA.

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