| Product Name |
16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase |
| Example Structure |
 |
| Synonyms |
16S rRNA adenine dimethyltransferase, KsgA, ksgA methyltransferase, RsmA, S-adenosylmethionine-6-N’,N’-adenosyl (rRNA) dimethyltransferase |
| EC Number |
2.1.1.182 |
| CAS Registry Number |
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| Comments |
KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine1518 and adenine1519 in 16S rRNA. Strains lacking the methylase are resistant to kasugamycin [1]. |
| Cofactor |
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| History |
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| Reactions |
4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)- dimethyladenine(1519) in 16S rRNA. |
