2-acylphloroglucinol 4-prenyltransferase EC#: 2.5.1.136; ChemWhat Code: 1378081
| Product Name | 2-acylphloroglucinol 4-prenyltransferase |
| Example Structure | ![]() |
| Synonyms | aromatic prenyltransferase, PT-1, PT1, PT1L |
| EC Number | 2.5.1.136 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from hop (Humulus lupulus), acts on phlorisovalerophenone, phlormethylbutanophenone, and phlorisobutanophenone during the synthesis of bitter acids. It also acts with much lower activity on naringenin chalcone. Forms a complex with EC 2.5.1.137, 2-acyl-4-prenylphloroglucinol 6-prenyltransferase, which catalyses additional prenylation reactions. Requires Mg2+. |
| Cofactor | Mg2+ |
| History | |
| Reactions | Dimethylallyl diphosphate + a 2-acylphloroglucinol = diphosphate + a 2-acyl-4-prenylphloroglucinol. |
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