2-alkenal reductase [NAD(P)+] EC#: 1.3.1.74; ChemWhat Code: 1374035

Product Name 2-alkenal reductase [NAD(P)+]
Example Structure Example Structure of 2-alkenal reductase [NAD(P)+] EC#: 1.3.1.74
Synonyms 2-alkenal reductase, 2AER, AER, alkenal/one oxidoreductase, alkenal/one reductase, AOR, At-AER, At5g16970, AtAOR, bifunctional LTB4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase, CS-670 double-bond reductase, CsAOR, Dbr1, double bond reductase, LTB4 12-HD/PGR, NADPH alkenal/one oxidoreductase, NADPH-dependent alkenal/one oxidoreductase
EC Number 1.3.1.74
CAS Registry Number 137367-20-5;57406-74-3;9032-20-6
Comments Highly specific for 4-hydroxynon-2-enal and non-2-enal. Alk-2-enals of shorter chain have lower affinities. Exhibits high activities also for alk-2-enones such as but-3-en-2-one and pent-3-en-2-one. Inactive with cyclohex-2-en-1-one and 12-oxophytodienoic acid. Involved in the detoxication of ¦Á,¦Â-unsaturated aldehydes and ketones [cf. EC 1.3.1.102, 2-alkenal reductase (NADP+)].
Cofactor
History
Reactions A n-alkanal + NAD(P)(+) = an alk-2-enal + NAD(P)H.

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