2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5′-monophosphate deformylase EC#: 3.5.1.102; ChemWhat Code: 1381310

Product Name 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5′-monophosphate deformylase
Example Structure Example Structure of 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase EC#: 3.5.1.102
Synonyms 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5′-monophosphate deformylase, ArfB, MJ0116
EC Number 3.5.1.102
CAS Registry Number
Comments The enzyme catalyses the second step in archaeal riboflavin and 7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthesis. The first step is catalysed by EC?3.5.4.29?(GTP cyclohydrolase IIa). The bacterial enzyme, EC?3.5.4.25?(GTP cyclohydrolase II) catalyses both reactions.
Cofactor
History
Reactions 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H(2)O = 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate.

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