2′-deamino-2′-hydroxyneamine 1-alpha-D-kanosaminyltransferase EC#: 2.4.1.301; ChemWhat Code: 1377633

Product Name 2′-deamino-2′-hydroxyneamine 1-alpha-D-kanosaminyltransferase
Example Structure Example Structure of 2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase EC#: 2.4.1.301
Synonyms KanE, KanM2
EC Number 2.4.1.301
CAS Registry Number
Comments Involved in the biosynthetic pathway of kanamycins. The enzyme characterized from the bacterium Streptomyces kanamyceticus can also accept UDP-¦Á-D-glucose with lower efficiency [2].
Cofactor
History
Reactions (1) UDP-alpha-D-kanosamine + 2′-deamino-2′-hydroxyneamine = Udp + kanamycin A. (2) UDP-alpha-D-kanosamine + neamine = Udp + kanamycin b. (3) UDP-alpha-D-kanosamine + paromamine = Udp + kanamycin c. (4) UDP-alpha-D-kanosamine + 2′-deamino-2′-hydroxyparomamine = Udp + kanamycin X.

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