2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) EC#: 1.1.99.38; ChemWhat Code: 1373716

Product Name 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
Example Structure Example Structure of 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) EC#: 1.1.99.38
Synonyms BtrN, DOIA dehydrogenase
EC Number 1.1.99.38
CAS Registry Number
Comments Involved in the biosynthetic pathway of the aminoglycoside antibiotics of the butirosin family. The enzyme from Bacillus circulans was shown to be a radical S-adenosyl-L-methionine (SAM) enzyme. cf. EC 1.1.1.329, 2-deoxy-scyllo-inosamine dehydrogenase.
Cofactor iron-sulfur
History
Reactions 2-deoxy-scyllo-inosamine + S-adenosyl-L-methionine = 3-amino-2,3-dideoxy- scyllo-inosose + 5′-deoxyadenosine + L-methionine.

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