2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) EC#: 1.1.99.38; ChemWhat Code: 1373716
| Product Name | 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) |
| Example Structure |  |
| Synonyms | BtrN, DOIA dehydrogenase |
| EC Number | 1.1.99.38 |
| CAS Registry Number | |
| Comments | Involved in the biosynthetic pathway of the aminoglycoside antibiotics of the butirosin family. The enzyme from Bacillus circulans was shown to be a radical S-adenosyl-L-methionine (SAM) enzyme. cf. EC 1.1.1.329, 2-deoxy-scyllo-inosamine dehydrogenase. |
| Cofactor | iron-sulfur |
| History | |
| Reactions | 2-deoxy-scyllo-inosamine + S-adenosyl-L-methionine = 3-amino-2,3-dideoxy- scyllo-inosose + 5′-deoxyadenosine + L-methionine. |
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