2-deoxystreptamine N-acetyl-D-glucosaminyltransferase EC#: 2.4.1.283; ChemWhat Code: 1377609
| Product Name | 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase |
| Example Structure |  |
| Synonyms | btrM, kanF, neoD |
| EC Number | 2.4.1.283 |
| CAS Registry Number | |
| Comments | Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Unlike the enzyme from the bacterium Streptomyces kanamyceticus, which can also accept UDP-D-glucose [2] (cf. EC 2.4.1.284, 2-deoxystreptamine glucosyltransferase), the enzyme from Bacillus circulans can only accept UDP-N-acetyl-¦Á-D-glucosamine [1]. |
| Cofactor | |
| History | |
| Reactions | UDP-N-acetyl-alpha-D-glucosamine + 2-deoxystreptamine = Udp + 2′-N- acetylparomamine. |
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