2-haloacid dehalogenase (configuration-inverting) EC#: 3.8.1.10

Product Name 2-haloacid dehalogenase (configuration-inverting)
Example Structure Example Structure of 2-haloacid dehalogenase (configuration-inverting) EC#: 3.8.1.10
Synonyms 2-HAD, 2-haloalkanoic acid dehalogenase, 2-haloalkanoid acid halidohydrolase, DL DEX 113, DL-2-haloacid dehalogenase, DL-2-haloacid dehalogenase (inversion of configuration), DL-2-haloacid halidohydrolase (inversion of configuration), DL-DEX, DL-DEX 113, DL-DEX Mb, DL-DEXi, L-2-haloacid dehalogenase, L-DEX YL, ps-2-HAD
EC Number 3.8.1.10
CAS Registry Number
Comments Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the corresponding (R)- and (S)-hydroxyalkanoic acids, respectively, with inversion of configuration at C-2. The enzyme from?Pseudomonas?sp. 113 acts on 2-haloalkanoic acids whose carbon chain lengths are five or less. [See also EC?3.8.1.2, (S)-2-haloacid dehalogenase, EC?3.8.1.9, (R)-2-haloacid dehalogenase and EC?3.8.1.11, 2-haloacid dehalogenase (configuration-retaining)].
Cofactor
History
Reactions (1) (S)-2-haloacid + H(2)O = (R)-2-hydroxyacid + halide. (2) (R)-2-haloacid + H(2)O = (S)-2-hydroxyacid + halide.

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