2-halobenzoate 1,2-dioxygenase EC#: 1.14.12.13; ChemWhat Code: 1375183

Product Name 2-halobenzoate 1,2-dioxygenase
Example Structure Example Structure of 2-halobenzoate 1,2-dioxygenase EC#: 1.14.12.13
Synonyms (chloro)benzoate dioxygenase, 2-chlorobenzoate 1,2-dioxygenase, 2-halobenzoate 1,2-dioxygenase, 2-halobenzoate dioxygenase, 2-halobenzoate dioxygenase system, BenA, CbdAB, cbdABC
EC Number 1.14.12.13
CAS Registry Number 125268-83-9
Comments A multicomponent enzyme system composed of a dioxygenase component and an electron transfer component. The latter contains FAD. The enzyme, characterized from the bacterium Burkholderia cepacia 2CBS, has a broad substrate specificity. Substrates include 2-fluorobenzoate, 2-chlorobenzoate, 2-bromobenzoate, and 2-iodobenzoate, which are processed in this order of preference.
Cofactor Fe cation
History
Reactions A 2-halobenzoate + nadh + O(2) = catechol + a halide anion + NAD(+) + CO(2).

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