2-methylcitrate dehydratase EC#: 4.2.1.79; ChemWhat Code: 1382356

Product Name 2-methylcitrate dehydratase
Example Structure Example Structure of 2-methylcitrate dehydratase EC#: 4.2.1.79
Synonyms 2-MC dehydratase, 2-methylcitrate dehydratase, 2-methylcitrate dehydratase 1, 2-Methylcitrate hydro-lyase, Dehydratase, 2-methylcitrate, methylcitrate dehydratase, mmgE, PrpD, SePrpD, STM0370
EC Number 4.2.1.79
CAS Registry Number 80891-26-5
Comments The enzyme is specific for (2S,3S)-methylcitrate, showing no activity with (2R,3S)-methylcitrate [2]. The enzyme can also use?cis-aconitate as a substrate but more slowly [2]. Both this enzyme and EC?4.2.1.3, aconitate hydratase, are required to complete the isomerization of (2S,3S)-methylcitrate to (2R,3S)-2-methylisocitrate [2].
Cofactor
History
Reactions (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3- tricarboxylate + H(2)O.

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