2-methylcitrate synthase EC#: 2.3.3.5; ChemWhat Code: 1377200
| Product Name | 2-methylcitrate synthase |
| Example Structure |  |
| Synonyms | 2-MC synthase, 2-MCS, 2-MCS1, 2-methylcitrate oxaloacetate-lyase, 2-methylcitrate synthase 2, citrate synthase II, EC 4.1.3.31, MCA condensing enzyme, MCS, Methylcitrate synthase, methylcitrate synthetase, MscA, PrpC, prpC2, Rv1131 |
| EC Number | 2.3.3.5 |
| CAS Registry Number | 57827-78-8 |
| Comments | The enzyme acts on acetyl-CoA, propanoyl-CoA, butanoyl-CoA and pentanoyl-CoA. The relative rate of condensation of acetyl-CoA and oxaloacetate is 140% of that of propanoyl-CoA and oxaloacetate, but the enzyme is distinct from EC 2.3.3.1, citrate (Si)-synthase. Oxaloacetate cannot be replaced by glyoxylate, pyruvate or 2-oxoglutarate. |
| Cofactor | |
| History | |
| Reactions | Propanoyl-CoA + H(2)O + oxaloacetate = (2S,3S)-2-hydroxybutane-1,2,3- tricarboxylate + CoA. |
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