2-oxoglutarate reductase EC#: 1.1.1.399; ChemWhat Code: 1373530
| Product Name | 2-oxoglutarate reductase |
| Example Structure |  |
| Synonyms | |
| EC Number | 1.1.1.399 |
| CAS Registry Number | |
| Comments | The enzyme catalyses a reversible reaction. The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate [1,2]. The SerA enzyme from Escherichia coli can also accept (S)-2-hydroxyglutarate with a much higher Km, and also catalyses the activity of EC 1.1.1.95, phosphoglycerate dehydrogenase [3]. |
| Cofactor | |
| History | |
| Reactions | (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + Nadh. |
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