23S rRNA (adenine2085-N6)-dimethyltransferase EC#: 2.1.1.184; ChemWhat Code: 1376401
| Product Name | 23S rRNA (adenine2085-N6)-dimethyltransferase |
| Example Structure |  |
| Synonyms | 23S ribosomal RNA adenine N-6 methyltransferase, ErmC, ermC 23 S rRNA methyltransferase, ErmC 23S rRNA methyltransferase, ermC methylase, ErmC methyltransferase, ErmC’, ErmC’ methyltransferase, ErmC’ MTase, erythromycin resistance protein, rRNA methyltransferase ErmC’, rRNA:m6A methyltransferase ErmC’ |
| EC Number | 2.1.1.184 |
| CAS Registry Number | |
| Comments | ErmC is a methyltransferase that confers resistance to the macrolide-lincosamide-streptogramin B group of antibiotics by catalysing the methylation of 23S rRNA at adenine2085. |
| Cofactor | |
| History | |
| Reactions | 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L- homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA. |
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