23S rRNA (guanine2445-N2)-methyltransferase EC#: 2.1.1.173; ChemWhat Code: 1376381
| Product Name | 23S rRNA (guanine2445-N2)-methyltransferase |
| Example Structure |  |
| Synonyms | 23S RNA m(2)G2445 methyltransferase, m2G2445 methyltransferase, ribosomal large subunit methyltransferase, RlmKL, RlmL, Smu472, ycbY |
| EC Number | 2.1.1.173 |
| CAS Registry Number | |
| Comments | The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate [1]. The enzyme specifically methylates guanine2445 at N2 in 23S rRNA. |
| Cofactor | |
| History | |
| Reactions | S-adenosyl-L-methionine + guanine(2445) in 23S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(2445) in 23S rRNA. |
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