2,4-diaminopentanoate dehydrogenase EC#: 1.4.1.12; ChemWhat Code: 1374265

Product Name 2,4-diaminopentanoate dehydrogenase
Example Structure Example Structure of 2,4-diaminopentanoate dehydrogenase EC#: 1.4.1.12
Synonyms 2,4-DAPDH, 2,4-diaminopentanoic acid C4 dehydrogenase, 2R,4S-2,4-diaminopentanoate dehydrogenase, DAPDH
EC Number 1.4.1.12
CAS Registry Number 39346-26-4
Comments Also acts, more slowly, on 2,5-diaminohexanoate forming 2-amino-5-oxohexanoate, which then cyclizes non-enzymically to 1-pyrroline-2-methyl-5-carboxylate. It has equal activity with NAD+ and NADP+ [cf. EC 1.4.1.26, 2,4-diaminopentanoate dehydrogenase (NAD+)].
Cofactor
History
Reactions (2R,4S)-2,4-diaminopentanoate + H(2)O + NAD(P)(+) = (2R)-2-amino-4- oxopentanoate + NH(3) + NAD(P)H.

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