2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5′-phosphate reductase EC#: 1.1.1.302; ChemWhat Code: 1373408

Product Name 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5′-phosphate reductase
Example Structure Example Structure of 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase EC#: 1.1.1.302
Synonyms 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5′-phosphate synthase, 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5′-phosphate reductase, arfC, MJ0671, MJ0671 pyrimidine reductase, MjaRED, ribD2
EC Number 1.1.1.302
CAS Registry Number
Comments The reaction proceeds in the opposite direction. A step in riboflavin biosynthesis, NADPH and NADH function equally well as reductant. Differs from EC 1.1.1.193 (5-amino-6-(5-phosphoribosylamino)uracil reductase) since it does not catalyse the reduction of 5-amino-6-ribosylaminopyrimidine-2,4(1H,3H)-dione 5′-phosphate [1].
Cofactor
History
Reactions 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + NAD(P)(+) = 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + NAD(P)H.

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