3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate-CoA ligase EC#: 6.2.1.41; ChemWhat Code: 1383649

Product Name 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate-CoA ligase
Example Structure Example Structure of 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate-CoA ligase EC#: 6.2.1.41
Synonyms fadD3, HIP-CoA ligase
EC Number 6.2.1.41
CAS Registry Number
Comments The enzyme, characterized from actinobacterium?Mycobacterium tuberculosis, catalyses a step in the degradation of cholesterol and cholate. The enzyme is very specific for its substrate, and requires that the side chain at C17 is completely removed.
Cofactor
History
Reactions Atp + 3-((3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4- yl)propanoate + CoA = Amp + diphosphate + 3-((3aS,4S,7aS)-7a-methyl-1,5- dioxo-octahydro-1H-inden-4-yl)propanoyl-CoA.

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