3-dehydroquinate synthase II EC#: 1.4.1.24; ChemWhat Code: 1374283
Product Name
3-dehydroquinate synthase II
Example Structure
Synonyms
aroB’, aroB2, dehydroquinate synthase II, DHQ synthase, DHQ synthase II, DHQS, MJ1249, MJ1249 protein, type II 3-dehydroquinate synthase
EC Number
1.4.1.24
CAS Registry Number
Comments
The enzyme, which was isolated from the archaeon Methanocaldococcus jannaschii, plays a key role in an alternative pathway for the biosynthesis of 3-dehydroquinate (DHQ), an intermediate of the canonical pathway for the biosynthesis of aromatic amino acids. The enzyme catalyses a two-step reaction – an oxidative deamination, followed by cyclization.
