3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase EC#: 2.5.1.132; ChemWhat Code: 1378077
| Product Name | 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase |
| Example Structure |  |
| Synonyms | 2-keto-3-deoxy-D-glycero-D-galacto-9-phosphonononic acid synthase, 2-keto-3-deoxy-D-glycero-D-galacto-nonulosonic acid 9-phosphate synthase, 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase, BT1714, KDN 9-phosphate synthase, KDN-9-P synthase, KDN-9-phosphate synthetase, KDN-9P synthase, N-acetylneuraminic acid phosphate synthase, Neu5Ac 9-phosphate synthase, neu5ac-9-P synthase, NeuNAc-9-P synthase |
| EC Number | 2.5.1.132 |
| CAS Registry Number | |
| Comments | The enzyme participates in the biosynthesis of the sialic acid 3-deoxy-D-glycero-D-galacto-nononate (KDN). The human sialic acid synthase (EC 2.5.1.57) is also able to catalyse the reaction. KDN is abundant in extracellular glycoconjugates of lower vertebrates such as fish and amphibians, but is also found in the capsular polysaccharides of bacteria that belong to the Bacteroides genus. |
| Cofactor | |
| History | |
| Reactions | Phosphoenolpyruvate + D-mannose 6-phosphate + H(2)O = 3-deoxy-D-glycero- D-galacto-nononate 9-phosphate + phosphate. |
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