3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase EC#: 1.13.11.48; ChemWhat Code: 1374968

Product Name 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase
Example Structure Example Structure of 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase EC#: 1.13.11.48
Synonyms 1H-3-Hydroxy-4-oxoquinaldine 2,4-dioxygenase, 1H-3-hydroxy-4-oxoquinaldine oxygenase, 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase, HOD, HodC, More
EC Number 1.13.11.48
CAS Registry Number
Comments Does not contain a metal centre or organic cofactor. Fission of two C-C bonds: 2,4-dioxygenolytic cleavage with concomitant release of carbon monoxide. The enzyme from Arthrobacter sp. can also act on 3-hydroxy-4-oxoquinoline, forming N-formylanthranilate and CO (cf. EC 1.13.11.47, 3-hydroxy-4-oxoquinoline 2,4-dioxygenase), but more slowly.
Cofactor
History
Reactions 3-hydroxy-2-methyl-1H-quinolin-4-one + O(2) = N-acetylanthranilate + Co.

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