3-isopropylmalate dehydrogenase EC#: 1.1.1.85; ChemWhat Code: 1373112
| Product Name | 3-isopropylmalate dehydrogenase |
| Example Structure |  |
| Synonyms | 2-hydroxy-4-methyl-3-carboxyvalerate:NAD+ oxidoreductase, 2R,3S-isopropylmalate:NAD+ oxidoreductase (decaboxylating), 3-IPM dehydrogenase, 3-IPM-DH, 3-isopropylmalate dehydrogenase, 3-isopropylmalateDH, APS IPMDH, beta-IPM dehydrogenase, beta-IPMDH, beta-isopropylmalate dehydrogenase, beta-isopropylmalic enzyme, Bs3-isopropylmalateDH, dehydrogenase, 3-isopropylmalate, IMDH, IPMDH, IPMDH1, IPMDH2, IPMDH3, isopropylmalate dehydrogenase, leuB, NAD-dependent isopropylmalate dehydrogenase, Saci_0600, SbIPMDH, SoIPMDH, threo-Ds-3-isopropylmalate dehydrogenase, Tt-beta-3-isopropylmalateDH, two-domain 3-isopropylmalate dehydrogenase, Ydr417cp |
| EC Number | 1.1.1.85 |
| CAS Registry Number | 9030-97-1 |
| Comments | The product decarboxylates spontaneously to yield 4-methyl-2-oxopentanoate. |
| Cofactor | |
| History | |
| Reactions | (2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + Nadh. |
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