3-(methylthio)propionyl-CoA ligase EC#: 6.2.1.44; ChemWhat Code: 1383652
| Product Name | 3-(methylthio)propionyl-CoA ligase |
| Example Structure | ![]() |
| Synonyms | 3-methylmercaptopropionyl-CoA ligase, BTH_DmdB2, BTH_I2141, DmdB, methylmercaptopropionate-coenzyme A ligase, MMPA-CoA ligase, PA4198, PA_DmdB1, PU_DmdB1, RL_DmdB1, RL_DmdB2, RPO_DmdB1, RPO_DmdB2, SAR11_0248, SL1157_1815, SL1157_2728, SPO0677, SPO2045 |
| EC Number | 6.2.1.44 |
| CAS Registry Number | |
| Comments | The enzyme is part of a dimethylsulfoniopropanoate demethylation pathway in the marine bacteria?Ruegeria pomeroyi?and?Pelagibacter ubique. It also occurs in some nonmarine bacteria capable of metabolizing dimethylsulfoniopropionate (e.g.?Burkholderia thailandensis,?Pseudomonas aeruginosa, and Silicibacter lacuscaerulensis). It requires Mg2+?[2]. |
| Cofactor | Mg2+ |
| History | |
| Reactions | Atp + 3-(methylthio)propanoate + CoA = amp + diphosphate + 3-(methylthio)propanoyl-CoA. |
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