3-[(Z)-2-isocyanoethenyl]-1H-indole synthase EC#: 1.14.20.11; ChemWhat Code: 1375854
| Product Name | 3-[(Z)-2-isocyanoethenyl]-1H-indole synthase |
| Example Structure | ![Example Structure of 3-[(Z)-2-isocyanoethenyl]-1H-indole synthase EC#: 1.14.20.11](/wp-content/uploads/enzyme-structure/1.14.20.11.jpg) |
| Synonyms | ambI3, famH3 |
| EC Number | 1.14.20.11 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from the cyanobacterium Fischerella ambigua UTEX 1903, participates in the biosynthesis of hapalindole-type alkaloids. The enzyme catalyses an Fe2+, 2-oxoglutarate-dependent monooxygenation at C-3, which is followed by decarboxylation and dehydration, resulting in the generation of a cis C-C double bond. cf. EC 1.14.20.12, L-tryptophan isonitrile desaturase/decarboxylase (3-[(E)-2-isocyanoethenyl]-1H-indole-forming). |
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