3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase EC#: 1.1.1.395; ChemWhat Code: 1373525
| Product Name | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase |
| Example Structure |  |
| Synonyms | |
| EC Number | 1.1.1.395 |
| CAS Registry Number | |
| Comments | This bacterial enzyme is involved in the 7-dehydroxylation process associated with bile acid degradation. The enzyme has very little activity with unconjugated bile acid substrates. It has similar activity with choloyl-CoA, chenodeoxycholoyl-CoA, deoxycholoyl-CoA, and lithocholoyl-CoA. Formerly EC 1.17.98.1. |
| Cofactor | |
| History | |
| Reactions | A 3-alpha-hydroxy bile acid CoA ester + NAD(+) = a 3-oxo bile acid CoA ester + Nadh. |
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