3alpha-hydroxycholanate dehydrogenase (NADP+) EC#: 1.1.1.392; ChemWhat Code: 1373522

Product Name 3alpha-hydroxycholanate dehydrogenase (NADP+)
Example Structure Example Structure of 3alpha-hydroxycholanate dehydrogenase (NADP+) EC#: 1.1.1.392
Synonyms
EC Number 1.1.1.392
CAS Registry Number
Comments This bacterial enzyme is involved in the modification of secondary bile acids to form 3¦Â-bile acids (also known as iso-bile acids) via a 3-oxo intermediate. The enzyme catalyses a reversible reaction in vitro. Also acts on related bile acids. cf. EC 1.1.1.52, 3¦Á-hydroxycholanate dehydrogenase (NAD+).
Cofactor
History
Reactions Lithocholate + NADP(+) = 3-oxo-5-beta-cholan-24-oate + Nadph.

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