3alpha-hydroxysteroid 3-dehydrogenase EC#: 1.1.1.357; ChemWhat Code: 1373476
| Product Name | 3alpha-hydroxysteroid 3-dehydrogenase |
| Example Structure |  |
| Synonyms | |
| EC Number | 1.1.1.357 |
| CAS Registry Number | |
| Comments | The enzyme acts on multiple 3¦Á-hydroxysteroids, such as androsterone and 5 ¦Á-dihydrotestosterone. The mammalian enzymes are involved in inactivation of steroid hormones, while the bacterial enzymes are involved in steroid degradation. This entry stands for enzymes whose stereo-specificity with respect to NAD+ or NADP+ is not known. [cf. EC 1.1.1.50, 3¦Á-hydroxysteroid 3-dehydrogenase (Si-specific) and EC 1.1.1.213, 3¦Á-hydroxysteroid 3-dehydrogenase (Re-specific)]. |
| Cofactor | |
| History | |
| Reactions | A 3-alpha-hydroxysteroid + NAD(P)(+) = a 3-oxosteroid + NAD(P)H. |
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