3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase EC#: 4.2.1.107; ChemWhat Code: 1382399

Product Name 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
Example Structure Example Structure of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase EC#: 4.2.1.107
Synonyms 46 kDa hydratase, 46 kDa hydratase 2, perMFE-2
EC Number 4.2.1.107
CAS Registry Number
Comments This enzyme forms part of the rat peroxisomal multifunctional enzyme perMFE-2, which also exhibits a dehydrogenase activity. The enzyme is involved in the ¦Â-oxidation of the cholesterol side chain in the cholic-acid-biosynthesis pathway.
Cofactor
History
Reactions (24R,25R)-3-alpha,7-alpha,12-alpha,24-tetrahydroxy-5-beta-cholestanoyl- CoA = (24E)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl- CoA + H(2)O.

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