3beta-hydroxycholanate 3-dehydrogenase (NADP+) EC#: 1.1.1.393; ChemWhat Code: 1373523
| Product Name | 3beta-hydroxycholanate 3-dehydrogenase (NADP+) |
| Example Structure |  |
| Synonyms | |
| EC Number | 1.1.1.393 |
| CAS Registry Number | |
| Comments | This bacterial enzyme is involved, along with EC 1.1.1.52, 3¦Á-hydroxycholanate dehydrogenase (NAD+), or EC 1.1.1.392, 3¦Á-hydroxycholanate dehydrogenase (NADP+), in the modification of secondary bile acids to form 3¦Â-bile acids (also known as iso-bile acids). The enzyme catalyses the reaction in the reduction direction in vivo. Also acts on related 3-oxo bile acids. cf. EC 1.1.1.391, 3¦Â-hydroxycholanate 3-dehydrogenase (NAD+). |
| Cofactor | |
| History | |
| Reactions | Isolithocholate + NADP(+) = 3-oxo-5-beta-cholan-24-oate + Nadph. |
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