Product Name |
4-amino-anhydrotetracycline N4-methyltransferase |
Example Structure |
 |
Synonyms |
ctcO, oxyT |
EC Number |
2.1.1.335 |
CAS Registry Number |
|
Comments |
The enzyme, characterized from the bacterium Streptomyces rimosus, participates in the biosynthesis of tetracycline antibiotics. |
Cofactor |
|
History |
|
Reactions |
(1) S-adenosyl-L-methionine + 4-amino-4- dedimethylaminoanhydrotetracycline = S-adenosyl-L-homocysteine + 4-methylamino-4-dedimethylaminoanhydrotetracycline. (2) S-adenosyl-L-methionine + 4-methylamino-4- dedimethylaminoanhydrotetracycline = S-adenosyl-L-homocysteine + anhydrotetracycline. |