(-)-4′-demethyl-deoxypodophyllotoxin 4-hydroxylase EC#: 1.14.14.132; ChemWhat Code: 1375640
Product Name | (-)-4′-demethyl-deoxypodophyllotoxin 4-hydroxylase |
Example Structure | |
Synonyms | CYP82D61 |
EC Number | 1.14.14.132 |
CAS Registry Number | |
Comments | A cytochrome P450 (heme-thiolate) protein characterized from the plant Sinopodophyllum hexandrum. The enzyme produces the direct precursor to etoposide, a potent anticancer drug. It can also act on (?)-deoxypodophyllotoxin with lower efficiency. Formerly EC 1.14.13.214. |
Cofactor | heme-thiolate |
History | |
Reactions |
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