4′-demethylrebeccamycin synthase EC#: 4.3.3.5; ChemWhat Code: 1382885
| Product Name | 4′-demethylrebeccamycin synthase |
| Example Structure |  |
| Synonyms | ngt, RebG |
| EC Number | 4.3.3.5 |
| CAS Registry Number | |
| Comments | This enzyme catalyses a step in the biosynthesis of rebeccamycin, an indolocarbazole alkaloid produced by the bacterium?Lechevalieria aerocolonigenes. The enzyme is a glycosylase, and acts in the reverse direction to that shown. It has a wide substrate range, and was shown to glycosylate several substrates, including the staurosporine aglycone, EJG-III-108A, J-104303, 6-N-methyl-arcyriaflavin C and indolo-[2,3-a]-carbazole [1,2]. |
| Cofactor | |
| History | |
| Reactions | 4′-O-demethylrebeccamycin + H(2)O = dichloro-arcyriaflavin A + beta-D- glucose. |
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