4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase EC#: 1.14.14.13; ChemWhat Code: 1375512

Product Name 4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase
Example Structure Example Structure of 4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase EC#: 1.14.14.13
Synonyms btrO
EC Number 1.14.14.13
CAS Registry Number
Comments Catalyses a step in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family. FMNH2 is used as a free cofactor. Forms a complex with a dedicated NAD(P)H:FMN oxidoreductase. The enzyme is not able to hydroxylate free substrates, activation by the acyl-carrier protein is mandatory. Octanoyl-S-[BtrI acyl-carrier protein] is also accepted.
Cofactor FMNH2
History
Reactions 4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] + FMNH(2) + O(2) = 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI acyl- carrier protein] + Fmn + H(2)O.

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