4-Hydrazinobenzoic acid hydrochloride CAS#: 24589-77-3; ChemWhat Code: 25290

IdentificationPhysical DataSpectra
Route of Synthesis (ROS)Safety and HazardsOther Data

Identification

Product Name4-Hydrazinobenzoic acid hydrochloride
IUPAC Name4-hydrazinylbenzoic acid;hydrochloride
Molecular StructureStructure of 4-Hydrazinobenzoic acid hydrochloride CAS 24589-77-3
CAS Registry Number 24589-77-3
EINECS Number246-330-0
MDL NumberMFCD00039073
Beilstein Registry NumberNo data available
Synonyms4-hydrazinobenzoic acid hydrochloride4-hydrazinylbenzoic acid hydrochloride4-carboxyphenylhydrazine hydrochloridep-hydrazinobenzoic acid hydrochloride
Molecular FormulaC7H9ClN2O2
Molecular Weight188.61
InChIInChI=1S/C7H8N2O2.ClH/c8-9-6-3-1-5(2-4-6)7(10)11;/h1-4,9H,8H2,(H,10,11);1H
InChI KeyXHLQMKQBCHYRLC-UHFFFAOYSA-N
Canonical SMILESc1cc(ccc1C(=O)O)NN.Cl
Patent Information
Patent IDTitlePublication Date
WO2021/13712POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES2021
EP4029501COMBINATION OF POLYAROMATIC UREA DERIVATIVES AND GLUCOCORTICOID OR HDAC INHIBITOR FOR THE TREATMENT OF DISEASES OR CONDITIONS ASSOCIATED WITH MUSCLE CELLS AND/OR SATELLITE CELLS2022
US2016/45512Inhibitors of Hemopoietic Cell Kinase (P59-HCK) and Their Use in the Treatment of Influenza Infection2016

Physical Data

AppearanceWhite solid
SolubilitySoluble in water.
Flash PointNo data available
Refractive indexNo data available
SensitivityNo data available
Melting Point, °CSolvent (Melting Point)Comment (Melting Point)
245with decomposition
248Decomposition.
252 – 253aq. HClDecomposition.
Measurement Temperature, °CType (Density)
-173.16crystallographic

Spectra

Description (IR Spectroscopy)Solvent (IR Spectroscopy)
Bandspotassium bromide
Description (Mass Spectrometry)
liquid chromatography mass spectrometry (LCMS), electrospray ionisation (ESI), spectrum

Route of Synthesis (ROS)

Route of Synthesis (ROS) of 4-Hydrazinobenzoic acid hydrochloride CAS# 24589-77-3
Route of Synthesis (ROS) of 4-Hydrazinobenzoic acid hydrochloride CAS# 24589-77-3
ConditionsYield
Stage #1: 4-amino-benzoic acid With magnesium nitrite In water at 2℃; Acidic conditions; Flow reactor;
Stage #2: With sodium sulfite In water at 99 – 120℃;
Stage #3: With hydrogenchloride In water at 120℃;
95%
Stage #1: 4-amino-benzoic acid With hydrogenchloride; sodium nitrite In water at 0℃;
Stage #2: With sulfuric acid In water at 0 – 5℃; for 12h;
91%
Stage #1: 4-amino-benzoic acid With hydrogenchloride; sodium nitrite In water at 0℃; for 0.5h;
Stage #2: With hydrogenchloride; tin(ll) chloride In water at 0℃; for 0.5h;

Safety and Hazards

Pictogram(s)exclamation-mark
SignalWarning
GHS Hazard StatementsH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Information may vary between notifications depending on impurities, additives, and other factors.
Precautionary Statement CodesP261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)

Other Data

TransportationNONH for all modes of transport
Under the room temperature and away from light
HS CodeNo data available
StorageStore in dry, in container tightly sealed; Protect from light.
Shelf Life1 year
Market PriceUSD
Druglikeness
Lipinski rules component
Molecular Weight188.614
logP0.903
HBA4
HBD3
Matching Lipinski Rules4
Veber rules component
Polar Surface Area (PSA)75.35
Rotatable Bond (RotB)2
Matching Veber Rules2
Use Pattern
4-Hydrazinobenzoic acid hydrochloride CAS#: 24589-77-3 is used as the Pharmaceutical Intermediates.

Buy Reagent

No reagent supplier? Send quick inquiry to ChemWhat
Want to be listed here as a reagent supplier? (Paid service) Click here to contact ChemWhat

Approved Manufacturers

Caming Pharmaceutical Ltdhttp://www.caming.com/
Want to be listed as an approved manufacturer (Requires approvement)? Please download and fill out this form and send back to approved-manufacturers@chemwhat.com

Contact Us for Other Help

Contact us for other information or services Click here to contact ChemWhat