4-hydroxy-2-oxohexanoate aldolase EC#: 4.1.3.43; ChemWhat Code: 1382183
| Product Name | 4-hydroxy-2-oxohexanoate aldolase |
| Example Structure |  |
| Synonyms | BphI, TTHB246 |
| EC Number | 4.1.3.43 |
| CAS Registry Number | |
| Comments | Requires Mn2+?for maximal activity [1,2]. The enzyme from the bacteria?Burkholderia xenovorans?and?Thermus thermophilus?also perform the reaction of EC?4.1.3.39, 4-hydroxy-2-oxovalerate aldolase [1,2,6]. The enzymes form a bifunctional complex with EC?1.2.1.89, propanal dehydrogenase (propanoylating), with a tight channel connecting the two subunits [3,4,6]. |
| Cofactor | Mn2+ |
| History | |
| Reactions | (S)-4-hydroxy-2-oxohexanoate = propanal + pyruvate. |
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