4-hydroxy-6-methylpretetramide 12a-monooxygenase EC#: 1.14.13.233; ChemWhat Code: 1375478
| Product Name | 4-hydroxy-6-methylpretetramide 12a-monooxygenase |
| Example Structure |  |
| Synonyms | oxyL |
| EC Number | 1.14.13.233 |
| CAS Registry Number | |
| Comments | Contains FAD. The enzyme, characterized from the bacterium Streptomyces rimosus, participates in the biosynthesis of tetracycline antibiotics. The enzyme is bifunctional, and can also catalyse EC 1.14.13.232, 6-methylpretetramide 4-monooxygenase. |
| Cofactor | FAD |
| History | |
| Reactions | 4-hydroxy-6-methylpretetramide + Nadph + O(2) = 4-dedimethylamino-4- oxoanhydrotetracycline + NADP(+) + H(2)O. |
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