4-hydroxyphenylacetate 3-monooxygenase EC#: 1.14.14.9; ChemWhat Code: 1375503
| Product Name | 4-hydroxyphenylacetate 3-monooxygenase |
| Example Structure |  |
| Synonyms | 4 HPA 3-hydroxyylase, 4-HPA hydroxylase, 4-hydroxyphenylacetate 3-hydroxylase, 4-hydroxyphenylacetic acid 3-hydroxylase, 4HPA 3-monooxygenase, 4HPA3H, C2-hpah, EC 1.14.13.3, HPA 3-hydroxylase, HpaB, hpaBC, HpaC, HPAH, More, p-hydroxyphenylacetate 3-hydroxylase, p-hydroxyphenylacetate hydroxylase, p-hydroxyphenylacetic 3-hydroxylase, two-component p-hydroxyphenylacetate hydroxylase |
| EC Number | 1.14.14.9 |
| CAS Registry Number | 37256-71-6 |
| Comments | The enzyme from Escherichia coli attacks a broad spectrum of phenolic compounds. The enzyme uses FADH2 as a substrate rather than a cofactor [4]. FADH2 is provided by EC 1.5.1.36, flavin reductase (NADH) [5,6]. |
| Cofactor | FAD |
| History | |
| Reactions | 4-hydroxyphenylacetate + FADH(2) + O(2) = 3,4-dihydroxyphenylacetate + Fad + H(2)O. |
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