4-nitrocatechol 4-monooxygenase EC#: 1.14.13.166; ChemWhat Code: 1375401
| Product Name | 4-nitrocatechol 4-monooxygenase |
| Example Structure |  |
| Synonyms | 4-nitrophenol 4-monooxygenase/4-nitrocatechol 2-monooxygenase, NpcA, npcB, NpdA2, p-nitrophenol monooxygenase, p-nitrophenol monooxygenase-II, para-nitrophenol 4-monooxygenase, PdcA, pentachlorophenol-4-monooxygenase, PNP 4-monooxygenase, PNP monooxygenase, pnpA, two-component PNP monooxygenase |
| EC Number | 1.14.13.166 |
| CAS Registry Number | |
| Comments | Contains FAD. The enzyme catalyses the oxidation of 4-nitrocatechol with the concomitant removal of the nitro group as nitrite. Forms a two-component system with a flavoprotein reductase [1]. The enzymes from the bacteria Lysinibacillus sphaericus JS905 and Rhodococcus sp. strain PN1 were shown to also catalyse EC 1.14.13.29, 4-nitrophenol 2-monooxygenase [1,2] while the enzyme from Pseudomonas sp. WBC-3 was shown to also catalyse EC 1.14.13.167, 4-nitrophenol 4-monooxygenase [3]. |
| Cofactor | FAD |
| History | |
| Reactions | 4-nitrocatechol + NAD(P)H + O(2) = 2-hydroxy-1,4-benzoquinone + nitrite + NAD(P)(+) + H(2)O. |
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