| Product Name |
5-(carboxyamino)imidazole ribonucleotide synthase |
| Example Structure |
 |
| Synonyms |
More, N5-CAIR synthetase, N5-carboxyaminoimidazole ribonucleotide synthetase, N5-carboxylaminoimidazole ribonucleotide synthetase, N5CAIR synthetase, PurK |
| EC Number |
6.3.4.18 |
| CAS Registry Number |
|
| Comments |
In?Escherichia coli, this enzyme, along with EC?5.4.99.18, 5-(carboxyamino)imidazole ribonucleotide mutase, is required to carry out the single reaction catalysed by EC?4.1.1.21, phosphoribosylaminoimidazole carboxylase, in vertebrates. Belongs to the ATP grasp protein superfamily [3]. Carboxyphosphate is the putative acyl phosphate intermediate. Involved in the late stages of purine biosynthesis. |
| Cofactor |
|
| History |
|
| Reactions |
Atp + 5-amino-1-(5-phospho-D-ribosyl)imidazole + HCO(3)(-) = adp + phosphate + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole. |
