5-hydroxydodecatetraenal polyketide synthase EC#: 2.3.1.281; ChemWhat Code: 1377118
| Product Name | 5-hydroxydodecatetraenal polyketide synthase |
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| Synonyms | cpkAB |
| EC Number | 2.3.1.281 |
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| Comments | This polyketide synthase enzyme, characterized from the bacterium Streptomyces coelicolor A3(2), catalyses the first reaction in the biosynthesis of coelimycin P1. The enzyme is made of three proteins which together comprise six modules that contain a total of 28 domains. An NADH-dependent terminal reductase domain at the C-terminus of the enzyme catalyses the reductive release of the product. |
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