5′ to 3′ exodeoxyribonuclease (nucleoside 3′-phosphate-forming) EC#: 3.1.12.1; ChemWhat Code: 1379709
| Product Name | 5′ to 3′ exodeoxyribonuclease (nucleoside 3′-phosphate-forming) |
| Example Structure |  |
| Synonyms | 5′ to 3′ single stranded DNA exonuclease, BH0340, Cas4, Cas4 nuclease, Cas4-1, Cas4-2, casC, CRISPR adaptation factor, CRISPR-associated Cas4 nuclease, CRISPR-associated exonuclease Cas4, CRISPR-associated protein 4, DUF83Pc, DUF83Ss, Pcal_0546, PF1119, PF1793, SSO0001, TTV1 nucleocapsid protein TP1, type I-C Cas4 |
| EC Number | 3.1.12.1 |
| CAS Registry Number | |
| Comments | Preference for single-stranded DNA. The enzyme from the archaeon?Sulfolobus solfataricus?contains a [4Fe-4S] cluster and requires a divalent metal cation, such as Mg2+?or Mn2+, for activity. |
| Cofactor | divalent metal cation;iron-sulfur |
| History | |
| Reactions | Exonucleolytic cleavage in the 5′- to 3′-direction to yield nucleoside 3′-phosphates. |
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