5a,11a-dehydrotetracycline reductase EC#: 1.3.98.4; ChemWhat Code: 1374187
| Product Name | 5a,11a-dehydrotetracycline reductase |
| Example Structure |  |
| Synonyms | 12-dehydrotetracycline dehydrogenase, 12-dehydrotetracycline reductase, dehydrooxytetracycline dehydrogenase, oxyR |
| EC Number | 1.3.98.4 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from the bacteria Streptomyces aureofaciens and Streptomyces rimosus, catalyses the last step in the biosynthesis of the tetracycline antibiotics tetracycline and oxytetracycline. |
| Cofactor | |
| History | |
| Reactions | Tetracycline + oxidized coenzyme F420 = 5a,11a-dehydrotetracycline + reduced coenzyme F420. |
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