5a,11a-dehydrotetracycline reductase EC#: 1.3.98.4; ChemWhat Code: 1374187

Product Name 5a,11a-dehydrotetracycline reductase
Example Structure Example Structure of 5a,11a-dehydrotetracycline reductase EC#: 1.3.98.4
Synonyms 12-dehydrotetracycline dehydrogenase, 12-dehydrotetracycline reductase, dehydrooxytetracycline dehydrogenase, oxyR
EC Number 1.3.98.4
CAS Registry Number
Comments The enzyme, characterized from the bacteria Streptomyces aureofaciens and Streptomyces rimosus, catalyses the last step in the biosynthesis of the tetracycline antibiotics tetracycline and oxytetracycline.
Cofactor
History
Reactions Tetracycline + oxidized coenzyme F420 = 5a,11a-dehydrotetracycline + reduced coenzyme F420.

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