(5R)-carbapenem-3-carboxylate synthase EC#: 1.14.20.3; ChemWhat Code: 1375845

Product Name (5R)-carbapenem-3-carboxylate synthase
Example Structure Example Structure of (5R)-carbapenem-3-carboxylate synthase EC#: 1.14.20.3
Synonyms carbapenem synthase, CarC
EC Number 1.14.20.3
CAS Registry Number
Comments Requires Fe2+. The enzyme is involved in the biosynthesis of the carbapenem ¦Â-lactam antibiotic (5R)-carbapen-2-em-3-carboxylate in the bacterium Pectobacterium carotovorum. It catalyses a stereoinversion at C5 and introduces a double bond between C-2 and C-3.
Cofactor Fe2+
History
Reactions (3S,5S)-carbapenam-3-carboxylate + 2-oxoglutarate + O(2) = (5R)-carbapen- 2-em-3-carboxylate + succinate + CO(2) + H(2)O.

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